PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21029677-1 2010 OBJECTIVE: To study the effect of pioglitazone, a synthetic peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, on the RANKL-mediated osteoclastogenesis of osteoclast precursor cells, and to explore the function and mechanism of PPARgamma in the osteoclast differentiation. Pioglitazone 34-46 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 137-142 27430581-0 2016 Pioglitazone affects the OPG/RANKL/RANK system and increase osteoclastogenesis. Pioglitazone 0-12 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 29-34 27430581-3 2016 The present study aimed to investigate the effect of pioglitazone (PIO), a thiazolidinedione, on osteoblastogenesis, osteoclastogenesis and the osteoprotegerin (OPG) / receptor activator of nuclear factor-kappaB ligand (RANKL) / RANK system. Pioglitazone 53-65 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 220-225 21029677-4 2010 And pioglitazone treated cells were exposed to 10 micromol/L pioglitazone during the process of osteoclast differentiation under RANKL. Pioglitazone 4-16 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 129-134 21029677-4 2010 And pioglitazone treated cells were exposed to 10 micromol/L pioglitazone during the process of osteoclast differentiation under RANKL. Pioglitazone 61-73 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 129-134