PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26643070-0 2016 Pioglitazone, a PPARgamma agonist, attenuates PDGF-induced vascular smooth muscle cell proliferation through AMPK-dependent and AMPK-independent inhibition of mTOR/p70S6K and ERK signaling. Pioglitazone 0-12 ribosomal protein S6 kinase B1 Homo sapiens 164-170 26643070-6 2016 In particular, PIO at 30muM concentration activates AMPK to induce raptor phosphorylation, which diminishes PDGF-induced mTOR activity as evidenced by decreased phosphorylation of p70S6K, 4E-BP1, and S6 and increased accumulation of p27(kip1), a cell cycle inhibitor. Pioglitazone 15-18 ribosomal protein S6 kinase B1 Homo sapiens 180-186