PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14686729-9	2003	In addition, apoptosis occurred in both cell lines treated with either PGZ or ATRA, which was associated with a downregulation of bcl-2 and an upregulation of bax proteins.	Pioglitazone	71-74	BCL2 associated X, apoptosis regulator	Homo sapiens	159-162	
32881246-8	2020	Pioglitazone also reduced the activation of caspase-3 and caspase-9, lowered the ratio of Bax/Bcl-2, attenuated kidney pathological damage and dysfunction, down-regulated the expression of Acetyl-p53, PUMA-alpha and Bax and abated cell apoptosis after cisplatin treatment.	Pioglitazone	0-12	BCL2 associated X, apoptosis regulator	Homo sapiens	90-93	
32881246-8	2020	Pioglitazone also reduced the activation of caspase-3 and caspase-9, lowered the ratio of Bax/Bcl-2, attenuated kidney pathological damage and dysfunction, down-regulated the expression of Acetyl-p53, PUMA-alpha and Bax and abated cell apoptosis after cisplatin treatment.	Pioglitazone	0-12	BCL2 associated X, apoptosis regulator	Homo sapiens	216-219