PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28443766-17	2003	The pretreatment with pioglitazone caused a significant up-regulation of mRNA and protein expression of leptin, reaching its peak at the dose 30 mg/kg i.g.	Pioglitazone	22-34	leptin	Rattus norvegicus	104-110	
12795455-17	2003	The pretreatment with pioglitazone caused a significant up-regulation of mRNA and protein expression of leptin, reaching its peak at the dose 30 mg/kg i.g.	Pioglitazone	22-34	leptin	Rattus norvegicus	104-110	
29212876-5	2018	In addition, activation of PPARgamma by pioglitazone or targeting ERK1/2/Egr-1 suppressed leptin-induced PASMC proliferation.	Pioglitazone	40-52	leptin	Rattus norvegicus	90-96	
26557974-6	2015	RESULTS: The experimental NASH rats treated with pioglitazone showed significant decrease in the levels of hyaluronic acid and significant increase in adiponectin levels when compared to experimentally induced NASH group, but did not show any effect on the levels of leptin.	Pioglitazone	49-61	leptin	Rattus norvegicus	267-273