PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31023188-3	2019	OBJECTIVE: We hypothesized that LRP1 (low-density lipoprotein receptor-related protein 1) expression is decreased in PAH, leading to enhancement (disinhibition) of TGFbeta1 signals and that the PPARgamma agonist pioglitazone can restore vascular homeostasis and prevent PAH resulting from LRP1 deletion in vascular smooth muscle cells (SMCs).	Pioglitazone	212-224	LDL receptor related protein 1	Homo sapiens	32-36	
31023188-3	2019	OBJECTIVE: We hypothesized that LRP1 (low-density lipoprotein receptor-related protein 1) expression is decreased in PAH, leading to enhancement (disinhibition) of TGFbeta1 signals and that the PPARgamma agonist pioglitazone can restore vascular homeostasis and prevent PAH resulting from LRP1 deletion in vascular smooth muscle cells (SMCs).	Pioglitazone	212-224	LDL receptor related protein 1	Homo sapiens	38-88	
31023188-9	2019	Downregulation of LRP1 protein was also demonstrated in explanted PASMC from patients with PAH and accompanied by enhanced TGFbeta1-pSmad3-CTGF signaling and increased TGFbeta1-induced PASMC proliferation that was prevented by pioglitazone.	Pioglitazone	227-239	LDL receptor related protein 1	Homo sapiens	18-22	
30867485-3	2019	We previously reported that low-dose pioglitazone increased the expression of low-density lipoprotein receptor-related protein 1 (LRP1), which upregulates the clearance of Abeta, using human brain microvascular endothelial cells.	Pioglitazone	37-49	LDL receptor related protein 1	Homo sapiens	78-128	
30867485-3	2019	We previously reported that low-dose pioglitazone increased the expression of low-density lipoprotein receptor-related protein 1 (LRP1), which upregulates the clearance of Abeta, using human brain microvascular endothelial cells.	Pioglitazone	37-49	LDL receptor related protein 1	Homo sapiens	130-134