PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33064289-0	2021	R-sulforaphane modulates the expression profile of AhR, ERalpha, Nrf2, NQO1, and GSTP in human breast cell lines.	sulforaphane	0-14	glutathione S-transferase pi 1	Homo sapiens	81-85	
19028145-3	2009	OBJECTIVE: We conducted a placebo-controlled dose escalation trial to investigate the in vivo effects of sulforaphane, a naturally occurring potent inducer of Phase II enzymes, on the expression of glutathione-s-transferase M1 (GSTM1), glutathione-s-transferase P1 (GSTP1), NADPH quinone oxidoreductase (NQO1), and hemoxygenase-1 (HO-1) in the upper airway of human subjects.	sulforaphane	105-117	glutathione S-transferase pi 1	Homo sapiens	236-264	
19028145-3	2009	OBJECTIVE: We conducted a placebo-controlled dose escalation trial to investigate the in vivo effects of sulforaphane, a naturally occurring potent inducer of Phase II enzymes, on the expression of glutathione-s-transferase M1 (GSTM1), glutathione-s-transferase P1 (GSTP1), NADPH quinone oxidoreductase (NQO1), and hemoxygenase-1 (HO-1) in the upper airway of human subjects.	sulforaphane	105-117	glutathione S-transferase pi 1	Homo sapiens	266-271	
18204073-4	2008	Compared with parental cells, expression of GSTP1-1 alone enhanced the rate of intracellular accumulation of SFN and its glutathione conjugate, SFN-SG--an effect that was associated with increased ARE-containing reporter gene induction.	sulforaphane	109-112	glutathione S-transferase pi 1	Homo sapiens	44-51	
18204073-7	2008	Depletion of GSH prior to SFN treatment or the substitution of tert-butylhydroquinone for SFN abolished the effects of MRP1/GSTP1-1 on ARE-containing gene induction-indicating that these effects are GSH dependent.	sulforaphane	90-93	glutathione S-transferase pi 1	Homo sapiens	124-131	
16778223-10	2006	After culture and in vitro exposure to sulforaphane, BITC, or EGCG, the elevated GSTP1 mRNA expression of PBMCs from HAP3 individuals decreased to common expression levels.	sulforaphane	39-51	glutathione S-transferase pi 1	Homo sapiens	81-86	
10814878-8	2000	The expression of QR and GSTP1-1 proteins were increased by 3 to 4-fold and 3 to 5-fold, respectively, for MCF-10F cells treated with sulforaphane (0.5-2.0 microM).	sulforaphane	134-146	glutathione S-transferase pi 1	Homo sapiens	25-32	
18204073-0	2008	Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane.	sulforaphane	122-134	glutathione S-transferase pi 1	Homo sapiens	23-30	
18204073-2	2008	Because SFN is a reactive electrophile--readily forming conjugates with glutathione (GSH)--we asked whether expression of glutathione S-transferase (GST) P1-1 and the GSH conjugate efflux pump, multidrug resistance or resistance-associated protein (MRP) 1, would significantly modify the cellular response to SFN exposure.	sulforaphane	8-11	glutathione S-transferase pi 1	Homo sapiens	122-158