PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33064289-0 2021 R-sulforaphane modulates the expression profile of AhR, ERalpha, Nrf2, NQO1, and GSTP in human breast cell lines. sulforaphane 0-14 glutathione S-transferase pi 1 Homo sapiens 81-85 19028145-3 2009 OBJECTIVE: We conducted a placebo-controlled dose escalation trial to investigate the in vivo effects of sulforaphane, a naturally occurring potent inducer of Phase II enzymes, on the expression of glutathione-s-transferase M1 (GSTM1), glutathione-s-transferase P1 (GSTP1), NADPH quinone oxidoreductase (NQO1), and hemoxygenase-1 (HO-1) in the upper airway of human subjects. sulforaphane 105-117 glutathione S-transferase pi 1 Homo sapiens 236-264 19028145-3 2009 OBJECTIVE: We conducted a placebo-controlled dose escalation trial to investigate the in vivo effects of sulforaphane, a naturally occurring potent inducer of Phase II enzymes, on the expression of glutathione-s-transferase M1 (GSTM1), glutathione-s-transferase P1 (GSTP1), NADPH quinone oxidoreductase (NQO1), and hemoxygenase-1 (HO-1) in the upper airway of human subjects. sulforaphane 105-117 glutathione S-transferase pi 1 Homo sapiens 266-271 16778223-10 2006 After culture and in vitro exposure to sulforaphane, BITC, or EGCG, the elevated GSTP1 mRNA expression of PBMCs from HAP3 individuals decreased to common expression levels. sulforaphane 39-51 glutathione S-transferase pi 1 Homo sapiens 81-86 18204073-0 2008 Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane. sulforaphane 122-134 glutathione S-transferase pi 1 Homo sapiens 23-30 18204073-2 2008 Because SFN is a reactive electrophile--readily forming conjugates with glutathione (GSH)--we asked whether expression of glutathione S-transferase (GST) P1-1 and the GSH conjugate efflux pump, multidrug resistance or resistance-associated protein (MRP) 1, would significantly modify the cellular response to SFN exposure. sulforaphane 8-11 glutathione S-transferase pi 1 Homo sapiens 122-158 18204073-4 2008 Compared with parental cells, expression of GSTP1-1 alone enhanced the rate of intracellular accumulation of SFN and its glutathione conjugate, SFN-SG--an effect that was associated with increased ARE-containing reporter gene induction. sulforaphane 109-112 glutathione S-transferase pi 1 Homo sapiens 44-51 18204073-7 2008 Depletion of GSH prior to SFN treatment or the substitution of tert-butylhydroquinone for SFN abolished the effects of MRP1/GSTP1-1 on ARE-containing gene induction-indicating that these effects are GSH dependent. sulforaphane 90-93 glutathione S-transferase pi 1 Homo sapiens 124-131 10814878-8 2000 The expression of QR and GSTP1-1 proteins were increased by 3 to 4-fold and 3 to 5-fold, respectively, for MCF-10F cells treated with sulforaphane (0.5-2.0 microM). sulforaphane 134-146 glutathione S-transferase pi 1 Homo sapiens 25-32