PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32761488-8	2021	In addition, TLR4, myeloid differentiation primary response gene 88 (MyD88), p-IKKbeta, p-p65, and NF-kappaB p65 in nuclei levels were significantly reduced by dioscin.	dioscin	160-167	myeloid differentiation primary response gene 88	Mus musculus	19-67	
32761488-8	2021	In addition, TLR4, myeloid differentiation primary response gene 88 (MyD88), p-IKKbeta, p-p65, and NF-kappaB p65 in nuclei levels were significantly reduced by dioscin.	dioscin	160-167	myeloid differentiation primary response gene 88	Mus musculus	69-74	
27135544-0	2016	Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.	dioscin	0-7	myeloid differentiation primary response gene 88	Mus musculus	89-94	
27135544-7	2016	TLR4 overexpression was also decreased by dioscin, leading to the markedly decreased levels of MyD88, IRAK1, TRAF6, p-IKK, p-IkappaBalpha, p-NF-kappaB p65 and HMGB-1.	dioscin	42-49	myeloid differentiation primary response gene 88	Mus musculus	95-100	
27135544-8	2016	Suppression of MyD88 by ST2825 eliminated the inhibitory effects of dioscin on the levels of IRAK1, TRAF6, p-IKK, p-IkappaBalpha, p-NF-kappaB p65, HMGB-1, IL-1beta, IL-6 and TNF-alpha.	dioscin	68-75	myeloid differentiation primary response gene 88	Mus musculus	15-20	
27135544-9	2016	Our results suggested that dioscin exhibited protective effect against LPS-induced liver injury via altering TLR4/MyD88 pathway, which should be developed as one potent candidate for the treatment of acute inflammatory liver injury in the future.	dioscin	27-34	myeloid differentiation primary response gene 88	Mus musculus	114-119	
27155058-6	2016	In addition, dioscin also inhibited TLR4/MyD88 pathway to decrease the levels of TRAF6 and the related proteins.	dioscin	13-20	myeloid differentiation primary response gene 88	Mus musculus	41-46	
29512786-0	2018	Dioscin prevents LPS-induced acute lung injury through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70.	dioscin	0-7	myeloid differentiation primary response gene 88	Mus musculus	75-80	
29512786-9	2018	The results suggested that dioscin prevents LPS-induced ALI through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70.	dioscin	27-34	myeloid differentiation primary response gene 88	Mus musculus	88-93