PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23607370-13 2013 The systemic inflammatory response triggered by intestinal IRI was significantly attenuated in mice pretreated with remifentanil (159 vs 805 pg/ml of IL-6 after saline pretreatment, with 92 pg/ml in the sham groups). Remifentanil 116-128 interleukin 6 Mus musculus 150-154 30167784-0 2018 Remifentanil suppresses increase in interleukin-6 mRNA in the brain by inhibiting cyclic AMP synthesis. Remifentanil 0-12 interleukin 6 Mus musculus 36-49 30167784-9 2018 RESULTS: Remifentanil suppressed increase in IL-6 mRNA levels in the mouse brain, and also inhibited the responses of plasma IL-6, corticosterone, and noradrenaline in an inflammatory state. Remifentanil 9-21 interleukin 6 Mus musculus 45-49 30167784-9 2018 RESULTS: Remifentanil suppressed increase in IL-6 mRNA levels in the mouse brain, and also inhibited the responses of plasma IL-6, corticosterone, and noradrenaline in an inflammatory state. Remifentanil 9-21 interleukin 6 Mus musculus 125-129 30167784-11 2018 In cultured cells, remifentanil suppressed increase in IL-6 mRNA levels and intracellular cAMP levels after the administration of LPS, and this enhanced IL-6 mRNA expression in response to LPS. Remifentanil 19-31 interleukin 6 Mus musculus 55-59 30167784-11 2018 In cultured cells, remifentanil suppressed increase in IL-6 mRNA levels and intracellular cAMP levels after the administration of LPS, and this enhanced IL-6 mRNA expression in response to LPS. Remifentanil 19-31 interleukin 6 Mus musculus 153-157 30167784-12 2018 CONCLUSION: Remifentanil suppressed increase in IL-6 mRNA levels in the brain in an inflammatory state, and this effect may be attributed to its direct action on neuronal cells through the inhibition of intracellular cAMP rather than corticosterone. Remifentanil 12-24 interleukin 6 Mus musculus 48-52