PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31065591-0 2019 Remifentanil promotes osteoblastogenesis by upregulating Runx2/osterix expression in preosteoblastic C2C12 cells. Remifentanil 0-12 Sp7 transcription factor 7 Mus musculus 63-70 31065591-8 2019 The expression of Runx2 and osterix was evaluated by RT-PCT and western blot analysis to investigate the mechanism involved in remifentanil-mediated osteoblast differentiation. Remifentanil 127-139 Sp7 transcription factor 7 Mus musculus 28-35 31065591-11 2019 RT-PCR and western blot analysis showed that the expression of Runx2 and osterix was upregulated by remifentanil. Remifentanil 100-112 Sp7 transcription factor 7 Mus musculus 73-80 31065591-12 2019 Conclusions: We demonstrated that remifentanil increased osteoblast differentiation in vitro by upregulation of Runx2 and osterix expression. Remifentanil 34-46 Sp7 transcription factor 7 Mus musculus 122-129