PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25241067-9 2014 Here, we found that the analgesic effect of remifentanil was followed by long-term hyperalgesia lasting at least postoperative 7 days, which was accompanied with increase in NR2B expression and trafficking from cytoplasm to surface and MnSOD nitration in dorsal horn. Remifentanil 44-56 superoxide dismutase 2 Rattus norvegicus 236-241 25241067-13 2014 In conclusion, HRS (10 ml/kg) might reverse remifentanil-induced hyperalgesia, through regulating NR2B-containing NMDAR trafficking to control MnSOD nitration and enhance MnSOD activity. Remifentanil 44-56 superoxide dismutase 2 Rattus norvegicus 143-148