PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31430547-8 2019 RESULTS: We reported that acute exposure to remifentanil caused and maintained behavioral RIH with up-regulation of expression in CCL7/CCR2 and IL-18/IL-18R and the phosphorylation of GluA1 in the dorsal horn. Remifentanil 44-56 C-C motif chemokine receptor 2 Rattus norvegicus 135-139 31430547-12 2019 CONCLUSION: Our current findings demonstrate that spinal CCL7/CCR2 modulation of GluA1-containing AMPA receptor activation via IL-18 and IL-18R over-expression is an important pathogenesis of remifentanil-induced hyperalgesia in rats. Remifentanil 192-204 C-C motif chemokine receptor 2 Rattus norvegicus 62-66