PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30863139-0	2019	TRPV1 channel contributes to remifentanil-induced postoperative hyperalgesia via regulation of NMDA receptor trafficking in dorsal root ganglion.	Remifentanil	29-41	transient receptor potential cation channel subfamily V member 1	Homo sapiens	0-5	
30863139-4	2019	However, the contribution of TRPV1 in modulating remifentanil-induced postoperative hyperalgesia is still unknown.	Remifentanil	49-61	transient receptor potential cation channel subfamily V member 1	Homo sapiens	29-34	
30863139-5	2019	The aim of this study is the contribution of TRPV1 to the surface expression of N-methyl-d-aspartate (NMDA) receptors in remifentanil-induced postoperative hyperalgesia.	Remifentanil	121-133	transient receptor potential cation channel subfamily V member 1	Homo sapiens	45-50	
30863139-11	2019	Here, we found the membrane trafficking of NR1, possibly due to the activation of TRPV1 in DRG neurons after remifentanil infusion.	Remifentanil	109-121	transient receptor potential cation channel subfamily V member 1	Homo sapiens	82-87	
30863139-12	2019	Furthermore, intrathecal injection of CPZ was able to relieve remifentanil-induced postoperative hyperalgesia according to a behavioral test and CPZ confirmed that TRPV1 is involved in NR1 trafficking.	Remifentanil	62-74	transient receptor potential cation channel subfamily V member 1	Homo sapiens	164-169	
30863139-14	2019	Conclusion: Our study demonstrates that TRPV1 receptors are involved in remifentanil-induced postoperative hyperalgesia.	Remifentanil	72-84	transient receptor potential cation channel subfamily V member 1	Homo sapiens	40-45	
30863139-15	2019	TRPV1 contributes to the persistence of remifentanil-induced postoperative hyperalgesia through the trafficking of NMDA receptors via the activation of CaMKII-PKC signaling pathways in DRG neurons.	Remifentanil	40-52	transient receptor potential cation channel subfamily V member 1	Homo sapiens	0-5