PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34486703-11 2021 CONCLUSIONS: Although RF does not exert direct pro-inflammatory actions on human adult microglia, its effects on BDNF, a crucial mediator of pain transmission, suggest a possible role on neuroinflammation and pain perception. Remifentanil 22-24 brain derived neurotrophic factor Homo sapiens 113-117