PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30430191-6	2019	Phosphorylation of Akt and activation of caspase 3 and poly (ADP-ribose) polymerase (PARP) partially reduced upon carfilzomib treatment in the presence of HS-5.	carfilzomib	114-125	caspase 3	Homo sapiens	41-83	
34281166-7	2021	Carfilzomib displayed potent antiproliferative effects, induced the unfolded protein response as determined by enhanced CHOP expression and ATF6 activity, and enhanced apoptosis as determined by enhanced caspase-3/7 activity.	carfilzomib	0-11	caspase 3	Homo sapiens	204-215	
33336554-11	2021	We found that carfilzomib alone significantly inhibited cell proliferation and induced apoptosis in a dose-dependent manner, characterized by the induction of cleaved caspase 3 and poly (ADP-ribose) polymerase.	carfilzomib	14-25	caspase 3	Homo sapiens	167-176	
30430191-10	2019	Caspase 3 activity increased while that of Akt decreased after combination treatment with copanlisib and carfilzomib.	carfilzomib	105-116	caspase 3	Homo sapiens	0-9