PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22889356-3 2013 NCTD inhibited the proliferation of MM cells and potentiated the anti-myeloma effects of BTZ by down-regulating IKKalpha and p-IkappaBalpha, which induced the accumulation of IkappaBalpha and inhibited the constitutive activation of NF-kappaB. Bortezomib 89-92 conserved helix-loop-helix ubiquitous kinase Mus musculus 112-120 34074311-12 2021 In db/db mice, PS-341 administration led to downregulation of Nur77/IKKbeta/NF-kappaB expression in visceral fat and liver, and alleviation of hyperglycaemia, hypertension, and glucose intolerance. Bortezomib 15-21 conserved helix-loop-helix ubiquitous kinase Mus musculus 68-75