PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32810966-2 2020 Methods: The expressions of Cdc37 and LC3b were investigated in BTZ-resistant MM cell line ANBL-6.BR using quantitative real-time PCR (qRT-PCR) and western blot (WB) analysis. Bortezomib 64-67 microtubule associated protein 1 light chain 3 beta Homo sapiens 38-42 32810966-9 2020 Results: Cdc37 was down-regulated, while autophagy-associated gene LC3b was upregulated in BTZ-resistant cell line ANBL-6.BR. Bortezomib 91-94 microtubule associated protein 1 light chain 3 beta Homo sapiens 67-71 20514020-5 2010 Previously, we have shown that Bortezomib-induced ATF4 stabilization, which then upregulated LC3B expression and had a critical role in activating autophagy, protecting cells from Bortezomib-induced cell death. Bortezomib 31-41 microtubule associated protein 1 light chain 3 beta Homo sapiens 93-97 19417138-8 2009 We show that induction of autophagy by Bortezomib is dependent on the proteasomal stabilisation of ATF4 and up-regulation of LC3B by ATF4. Bortezomib 39-49 microtubule associated protein 1 light chain 3 beta Homo sapiens 125-129 19417138-9 2009 We show that ATF4 and LC3B play a critical role in activating autophagy and protecting cells from Bortezomib-induced cell death. Bortezomib 98-108 microtubule associated protein 1 light chain 3 beta Homo sapiens 22-26