PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22082269-3	2011	We confirmed our previously discovered observation that bortezomib affects the expression of genes involved in the formation of MDR (ABCB1 gene, also known as MDR1, and ABCC1-MRP1), reducing the amount of their mRNA.	Bortezomib	56-66	ATP binding cassette subfamily C member 1	Homo sapiens	169-174	
22082269-3	2011	We confirmed our previously discovered observation that bortezomib affects the expression of genes involved in the formation of MDR (ABCB1 gene, also known as MDR1, and ABCC1-MRP1), reducing the amount of their mRNA.	Bortezomib	56-66	ATP binding cassette subfamily C member 1	Homo sapiens	175-179	
22082269-7	2011	It is shown that bortezomib affects the amount of MRP1 gene mRNA, relocating the multifunctional protein YB-1, dependent on Akt activity, from cytoplasm to nuclei of MCF-7 breast cancer cells.	Bortezomib	17-27	ATP binding cassette subfamily C member 1	Homo sapiens	50-54	
22082269-8	2011	The data indicate that the transcriptional activity of YB-1 might be one of the mechanisms that determine the effect of bortezomib on the amount of MRP1 gene mRNA.	Bortezomib	120-130	ATP binding cassette subfamily C member 1	Homo sapiens	148-152	
20532504-0	2010	Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin.	Bortezomib	179-189	ATP binding cassette subfamily C member 1	Homo sapiens	21-55	
20532504-7	2010	These findings suggest a potential role for MRP1 and MDR1 SNPs in modulating the long-term outcome of relapsed and/or refractory myeloma patients treated with PLD + bortezomib.	Bortezomib	165-175	ATP binding cassette subfamily C member 1	Homo sapiens	44-48	
20532504-3	2010	The MRP1/R723Q polymorphism was found in five subjects among the 279 patient study population, all of whom received PLD + bortezomib.	Bortezomib	122-132	ATP binding cassette subfamily C member 1	Homo sapiens	4-8