PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34262136-7 2022 We showed that in both models, diosmetin administration significantly decreased DAI score and ameliorated microscopic colon tissue damage; increased the expression of tight junction proteins (occludin, claudin-1, and zonula occludens-1), and reduced the secretion of proinflammatory cytokines IL-1beta, IL-6, TNF-alpha, and Cox-2 in colon tissue. diosmetin 31-40 interleukin 6 Mus musculus 303-307 24966921-6 2014 Pretreatment with diosmetin significantly reduced serum levels of amylase and lipase; the histological injury; the secretion of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6; myeloperoxidase (MPO) activity, trypsinogen activation peptide (TAP) level, the expression of inducible nitric oxide synthase (iNOS); and the nuclear factor (NF)-kappaB activation in cerulein-induced AP. diosmetin 18-27 interleukin 6 Mus musculus 191-195 33045572-11 2020 The mRNA analysis demonstrated that diosmetin also reduced the level of inflammatory cytokines such as IL-1beta and IL-6. diosmetin 36-45 interleukin 6 Mus musculus 116-120