PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30278036-11 2018 CONCLUSIONS Our study shows that diosmetin protects against renal injury in STZ-induced diabetic nephropathy mice by modulating the Akt/NF-kappaB/iNOS signaling pathway. diosmetin 33-42 thymoma viral proto-oncogene 1 Mus musculus 132-135 30825187-10 2019 Diosmetin induced ROS production in NSCLC cells probably via reducing Nrf2 stability through disruption of the PI3K/Akt/GSK-3beta pathway. diosmetin 0-9 thymoma viral proto-oncogene 1 Mus musculus 116-119 30825187-13 2019 CONCLUSIONS AND IMPLICATIONS: Diosmetin selectively induced apoptosis and enhanced the efficacy of paclitaxel in NSCLC cells via ROS accumulation through disruption of the PI3K/Akt/GSK-3beta/Nrf2 pathway. diosmetin 30-39 thymoma viral proto-oncogene 1 Mus musculus 177-180 30278036-0 2018 Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-kappaB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice. diosmetin 0-9 thymoma viral proto-oncogene 1 Mus musculus 21-24 30278036-9 2018 Expression of Akt and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) was significantly reduced and inducible nitric oxide synthase (iNOS) was enhanced in the tissue homogenate of diosmetin-treated mice compared to the negative control group. diosmetin 207-216 thymoma viral proto-oncogene 1 Mus musculus 14-17 34091150-0 2021 Diosmetin ameliorate type 2 diabetic mellitus by up-regulating Corynebacterium glutamicum to regulate IRS/PI3K/AKT-mediated glucose metabolism disorder in KK-Ay mice. diosmetin 0-9 thymoma viral proto-oncogene 1 Mus musculus 111-114 34091150-11 2021 Moreover, treatment with C. glu and Dios together could markedly ameliorate glucose metabolism by up-regulating IRS/PI3K/AKT signaling pathway to promote glycogen synthesis and GLUT4 translocation. diosmetin 36-40 thymoma viral proto-oncogene 1 Mus musculus 121-124