PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28101238-0	2016	Diosmetin triggers cell apoptosis by activation of the p53/Bcl-2 pathway and inactivation of the Notch3/NF-kappaB pathway in HepG2 cells.	diosmetin	0-9	nuclear factor kappa B subunit 1	Homo sapiens	104-113	
28101238-7	2016	Furthermore, by using small hairpin RNA-Notch3, it was confirmed that DIOS inhibited the NF-kappaB signaling pathway by inactivation of Notch3.	diosmetin	70-74	nuclear factor kappa B subunit 1	Homo sapiens	89-98	
31833613-0	2020	Diosmetin exhibits anti-proliferative and anti-inflammatory effects on TNF-alpha-stimulated human rheumatoid arthritis fibroblast-like synoviocytes through regulating the Akt and NF-kappaB signaling pathways.	diosmetin	0-9	nuclear factor kappa B subunit 1	Homo sapiens	179-188	
31833613-9	2020	Furthermore, diosmetin inhibited TNF-alpha-induced activation of protein kinase B (Akt) and nuclear factor-kappaB (NF-kappaB) pathways in MH7A cells.	diosmetin	13-22	nuclear factor kappa B subunit 1	Homo sapiens	92-113	
31833613-9	2020	Furthermore, diosmetin inhibited TNF-alpha-induced activation of protein kinase B (Akt) and nuclear factor-kappaB (NF-kappaB) pathways in MH7A cells.	diosmetin	13-22	nuclear factor kappa B subunit 1	Homo sapiens	115-124	
31833613-10	2020	Suppression of Akt or NF-kappaB promoted apoptosis and inhibited TNF-alpha-induced proliferation increase and production of IL-1beta, IL-6, IL-8, and MMP-1 in MH7A cells, and diosmetin treatment enhanced these effects.	diosmetin	175-184	nuclear factor kappa B subunit 1	Homo sapiens	22-31	
31833613-11	2020	Taken together, these findings suggested that diosmetin exhibited anti-proliferative and anti-inflammatory effects via inhibiting the Akt and NF-kappaB pathways in MH7A cells.	diosmetin	46-55	nuclear factor kappa B subunit 1	Homo sapiens	142-151	
32367620-4	2020	Diosmetin down-regulated the protein expression of inducible NO synthase in cocultured macrophages and adipocytes, and inhibited the phosphorylation of mitogen-activated protein kinases and the translocation of p65 and p50 to the nucleus.	diosmetin	0-9	nuclear factor kappa B subunit 1	Homo sapiens	219-222