PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28867436-4 2017 Diosmetin showed strong inhibition of CYP1A2 in a concentration-dependent manner. diosmetin 0-9 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 38-44 28867436-9 2017 This finding indicated that drug-drug interactions induced by diosmetin may occur through co-administration of drugs metabolized by CYP1A2. diosmetin 62-71 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 132-138 28245756-0 2017 Diosmetin Induces Cell Apoptosis by Regulating CYP1A1/CYP1A2 Due to p53 Activation in HepG2 Cells. diosmetin 0-9 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 54-60 18976853-4 2009 Diosmetin was metabolized to luteolin via an aromatic demethylation reaction on the B-ring from CYP1A1, CYP1B1 and the hepatic isozyme CYP1A2. diosmetin 0-9 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 135-141