PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32574665-0 2020 Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway. Luteolin 15-23 sirtuin 1 Homo sapiens 96-101 25057854-0 2014 Quercetin, luteolin, and epigallocatechin gallate promote glucose disposal in adipocytes with regulation of AMP-activated kinase and/or sirtuin 1 activity. Luteolin 11-19 sirtuin 1 Homo sapiens 136-145 25057854-5 2014 Quercetin, luteolin, and epigallocatechin gallate suppressed nuclear factor-kappaB activation by inhibition of p65 phosphorylation with beneficial regulation of adipokine expression, whereas these actions were diminished by coincubation with compound C. The sirtuin 1 inhibitor nicotinamide attenuated the effects of luteolin and EGCG on p65 phosphorylation and adipokine expression without any influence on the activity of quercetin. Luteolin 11-19 sirtuin 1 Homo sapiens 258-267 25057854-5 2014 Quercetin, luteolin, and epigallocatechin gallate suppressed nuclear factor-kappaB activation by inhibition of p65 phosphorylation with beneficial regulation of adipokine expression, whereas these actions were diminished by coincubation with compound C. The sirtuin 1 inhibitor nicotinamide attenuated the effects of luteolin and EGCG on p65 phosphorylation and adipokine expression without any influence on the activity of quercetin. Luteolin 317-325 sirtuin 1 Homo sapiens 258-267 25057854-7 2014 These findings suggested that quercetin, luteolin, and epigallocatechin gallate inhibited inflammation and promoted glucose disposal in adipocytes with the regulation of AMP-activated kinase and/or sirtuin 1. Luteolin 41-49 sirtuin 1 Homo sapiens 198-207 32574665-8 2020 SIGNIFICANCE: Thus, luteolin and lycopene in combination can effectively ameliorate "two-hit" in NAFLD through activation of the Sirt1/AMPK pathway. Luteolin 20-28 sirtuin 1 Homo sapiens 129-134