PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35212223-0	2022	Inhibition of HMGB1/TLR4 Signaling Pathway by Digitoflavone: A Potential Therapeutic Role in Alcohol-Associated Liver Disease.	Luteolin	46-59	high mobility group box 1	Mus musculus	14-19	
34607339-5	2021	Hence, we investigated the effects of luteolin, a natural flavonoid mainly existing in vegetables and fruits, on liver injury, focusing on how luteolin participates in hepatitis based on the P2X7R-RAGE-TLR4 axis by regulating the release of HMGB1.	Luteolin	38-46	high mobility group box 1	Mus musculus	241-246	
33015735-13	2021	qPCR and immunohistochemistry results showed that Lu significantly reduced HMGB1 mRNA level and protein level.	Luteolin	50-52	high mobility group box 1	Mus musculus	75-80	
33015735-14	2021	In addition, Lu significantly reduced the expression of HMGB1-TLR-NF-kappaB signaling pathway protein of intestine in mice.	Luteolin	13-15	high mobility group box 1	Mus musculus	56-61	
33015735-15	2021	In conclusion, Lu significantly reduced and alleviated DSS-induced colitis in mice, and the mechanism was related to the regulation of intestinal HMGB1-TLR-NF-kappaB signaling pathway in mice.	Luteolin	15-17	high mobility group box 1	Mus musculus	146-151