PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35600955-8 2022 Results: The network pharmacology analysis showed that quercetin, luteolin, and kaempferol are the most significant active components in BHHD; STAT3, Jun, AKT1, MAPK3, MAPK1, and TP53 are the most critical drug targets; regulating hormones, reversing insulin (INS) resistance, exerting anti-inflammatory effects, and improving fertility might be the most important mechanisms of BHHD in the treatment of PCOS. Luteolin 66-74 tumor protein p53 Homo sapiens 179-183 22749133-0 2013 The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. Luteolin 29-37 tumor protein p53 Homo sapiens 167-174 33757400-0 2022 Luteolin Induces Apoptosis and Autophagy in HCT116 Colon Cancer Cells via p53-Dependent Pathway. Luteolin 0-8 tumor protein p53 Homo sapiens 74-77 33757400-5 2022 Luteolin at 10 - 20 muM induced cytotoxicity in p53 wild-type HCT116 colon cancer cells but not in p53 mutant HT-29 cells and normal colon cells. Luteolin 0-8 tumor protein p53 Homo sapiens 48-51 33757400-7 2022 We identified that luteolin can induce autophagy in p53 wild-type cells but not in p53 mutant cells, suggesting that luteolin-induced autophagy is p53-dependent; however, chloroquine-mediated inhibition of autophagy did not alter cytotoxicity and apoptosis of cells treated with luteolin. Luteolin 19-27 tumor protein p53 Homo sapiens 52-55 31383362-9 2019 Also, luteolin induced oxidative stress and ER stress in p53-null Hep3B cells. Luteolin 6-14 tumor protein p53 Homo sapiens 57-60