PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34595237-7	2021	The results of molecular docking showed that AKT has the most binding activity, exhibiting certain binding activity with 10 compounds, including vanillic acid, protocatechuic acid, secologanic acid, quercetin, and luteolin; the results of qRT-PCR and WB confirmed that two key compounds, secologanic acid and luteolin, could significantly decrease the secretion of TNF-alpha and the AKT expression of RAW264.7 murine macrophages stimulated by LPS (lipopolysaccharide).	Luteolin	214-222	thymoma viral proto-oncogene 1	Mus musculus	45-48	
34671661-10	2021	Taken together, our study showed that the traditional Chinese medicine QJC, quercetin, luteolin, kaempferol, scutellarein, and stigmasterol alleviated the pathological condition of small intestine tissue and relieved stress-induced diarrhea by increasing the expression levels of PI3K and Akt and inhibiting the expression levels of PTEN.	Luteolin	87-95	thymoma viral proto-oncogene 1	Mus musculus	289-292	
34595237-7	2021	The results of molecular docking showed that AKT has the most binding activity, exhibiting certain binding activity with 10 compounds, including vanillic acid, protocatechuic acid, secologanic acid, quercetin, and luteolin; the results of qRT-PCR and WB confirmed that two key compounds, secologanic acid and luteolin, could significantly decrease the secretion of TNF-alpha and the AKT expression of RAW264.7 murine macrophages stimulated by LPS (lipopolysaccharide).	Luteolin	214-222	thymoma viral proto-oncogene 1	Mus musculus	383-386	
34595237-7	2021	The results of molecular docking showed that AKT has the most binding activity, exhibiting certain binding activity with 10 compounds, including vanillic acid, protocatechuic acid, secologanic acid, quercetin, and luteolin; the results of qRT-PCR and WB confirmed that two key compounds, secologanic acid and luteolin, could significantly decrease the secretion of TNF-alpha and the AKT expression of RAW264.7 murine macrophages stimulated by LPS (lipopolysaccharide).	Luteolin	309-317	thymoma viral proto-oncogene 1	Mus musculus	45-48	
34595237-7	2021	The results of molecular docking showed that AKT has the most binding activity, exhibiting certain binding activity with 10 compounds, including vanillic acid, protocatechuic acid, secologanic acid, quercetin, and luteolin; the results of qRT-PCR and WB confirmed that two key compounds, secologanic acid and luteolin, could significantly decrease the secretion of TNF-alpha and the AKT expression of RAW264.7 murine macrophages stimulated by LPS (lipopolysaccharide).	Luteolin	309-317	thymoma viral proto-oncogene 1	Mus musculus	383-386	
22843013-8	2013	Quercetin, luteolin, and EGCG inhibited inflammation-evoked IKKbeta activation and IRS-1 serine phosphorylation in adipose tissue, and thereby effectively restored glucose load-stimulated IRS-1 tyrosine and Akt phosphorylation, leading to an increase in insulin-mediated glucose uptake in adipocytes.	Luteolin	11-19	thymoma viral proto-oncogene 1	Mus musculus	207-210	
22843013-5	2013	Luteolin and EGCG, but not quercetin, inhibited glucose load-induced insulin receptor substrate-1(IRS-1) tyrosine and Akt phosphorylation in adipose tissue.	Luteolin	0-8	thymoma viral proto-oncogene 1	Mus musculus	118-121	
21513709-0	2011	Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-kappaB translocation in LPS stimulated RAW 264.7 cells.	Luteolin	0-8	thymoma viral proto-oncogene 1	Mus musculus	101-104	
21513709-5	2011	Luteolin and chicoric acid co-treatment inhibited phosphorylation of NF-kappaB and Akt, but had no effect on extracellular signal-regulated kinase (ERK), c-Jun NH2-terminal kinase (JNK), and p38.	Luteolin	0-8	thymoma viral proto-oncogene 1	Mus musculus	83-86