PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34493195-7 2022 RESULTS: We filtered out 6 pivotal ingredients from QFPDD by using the bioinformatics method, namely quercetin, luteolin, berberine, hederagenin, shionone and kaempferol, which can inhibit the highly expressed genes (i.e. CXCR4, ICAM1, CXCL8, CXCL10, IL6, IL2, CCL2, IL1B, IL4, IFNG) in severe COVID-19 patients. Luteolin 112-120 C-C motif chemokine ligand 2 Homo sapiens 261-265 35623848-6 2022 The bioactive compounds including luteolin, epicatechin, epigallocatechin gallate, lycopene, quercetin, vitamin A, vitamin C and vitamin E in FBV significantly lowered TNF-alpha production, CCL2 production, IL-1beta production, and reactive oxygen species production. Luteolin 34-42 C-C motif chemokine ligand 2 Homo sapiens 190-194 33520015-11 2020 Finally, 6 key proteins of TNF, IL-10, IL-2, IL-6, STAT1 and CCL2 were selected and successfully docked with 4 active ingredients of quercetin, luteolin, wogonin and kaempferol. Luteolin 144-152 C-C motif chemokine ligand 2 Homo sapiens 61-65 35372072-15 2022 Luteolin and quercetin may be the core active ingredients of QYSLS in the treatment of EGFRI-related adverse skin reactions, and their therapeutic effects are potentially mediated through PTGS2, CCL2, and MMP9 in the IL-17 and TNF signaling pathway. Luteolin 0-8 C-C motif chemokine ligand 2 Homo sapiens 195-199 31665675-7 2019 Therefore, combined curcumin and luteolin at physiological concentrations synergistically inhibits TNF-alpha-induced monocytes adhesion to endothelial cells and expressions of MCP-1 and VCAM-1 via suppressing NF-kappaB translocation into the nucleus. Luteolin 33-41 C-C motif chemokine ligand 2 Homo sapiens 176-181