PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22284780-11	2012	Specifically, apiegenin, baicalein, curcumin, EGCG, genistein, luteolin, oridonin, quercetin, and wogonin repress NF-kappaB (NF-kappaB, a proinflammatory transcription factor) and inhibit proinflammatory cytokines such as TNF-alpha and IL-6.	Luteolin	63-71	nuclear factor kappa B subunit 1	Homo sapiens	114-123	
31665675-5	2019	We also found that TNF-alpha-enhanced protein expressions of vascular cell adhesion molecule 1 (VCAM-1), monocyte chemotactic protein-1 (MCP-1) and nuclear factor (NF)-kappaB translocation were synergistically reduced by the combined curcumin and luteolin in EA.hy 926 cells while the individual chemical did not have this inhibitory effect.	Luteolin	247-255	nuclear factor kappa B subunit 1	Homo sapiens	148-174	
22284780-11	2012	Specifically, apiegenin, baicalein, curcumin, EGCG, genistein, luteolin, oridonin, quercetin, and wogonin repress NF-kappaB (NF-kappaB, a proinflammatory transcription factor) and inhibit proinflammatory cytokines such as TNF-alpha and IL-6.	Luteolin	63-71	nuclear factor kappa B subunit 1	Homo sapiens	125-134	
34889224-8	2021	The molecular docking results showed the components that docked well with key targets were quercetin, luteolin, kaempferol, and baicalein.The active components (quercetin, luteolin, kaempferol, and baicalein) of the RPR-FC and their targets act on proteins such as MAPK1, AKT1, VEGFA, and CASP3, which are closely related to IS.1 These targets are closely related to the NF-kappa B signaling pathway, the MAPK signaling pathway, the PI3K-Akt signaling pathway, the VEGF signaling pathway, and other signaling pathways.	Luteolin	172-180	nuclear factor kappa B subunit 1	Homo sapiens	371-381	
19739098-3	2009	Based on our previous observations that the nutrient flavonoid luteolin potently blocks TNF-induced NF-kappaB activation in cancer cells, we investigated if the combination of SMC3 and luteolin would achieve a synergistic anticancer activity.	Luteolin	63-71	nuclear factor kappa B subunit 1	Homo sapiens	100-109	
17296806-3	2007	Luteolin, a naturally occurring polyphenol flavonoid, has been reported to sensitize colorectal cancer cells to TNF-induced apoptosis through suppression of NF-kappaB; however, the mechanisms of this effect have not been well elucidated.	Luteolin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	157-166	
34785108-12	2022	Metascape enrichment analysis showed that 25 genes were significantly enriched in the NF-kappaB pathway, which were mainly targets of luteolin, quercetin, and kaempferol as confirmed by MS analysis.	Luteolin	134-142	nuclear factor kappa B subunit 1	Homo sapiens	86-95	
32017949-13	2020	Moreover, luteolin and kaempferol, the main activity compounds in MHF, significantly inhibited TNF-alpha-induced HPMVEC apoptosis, and downregulated NF-kappaB/MLCK pathway by targeting NOX4.	Luteolin	10-18	nuclear factor kappa B subunit 1	Homo sapiens	149-158