PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33335556-8 2020 In addition, luteolin treatment significantly upregulated the expression of Bcl-2 and downregulated the expression of Bax and caspase-3, whereas fulvestrant and U0126 partially reversed the effects of luteolin. Luteolin 13-21 BCL2 associated X, apoptosis regulator Rattus norvegicus 118-121 34804174-11 2021 We also found that caspase-3, caspase-8, and Bax were significantly upregulated and Bcl-2 was downregulated after LUT treatment. Luteolin 114-117 BCL2 associated X, apoptosis regulator Rattus norvegicus 45-48 32903480-7 2020 In addition, Lut inhibited Dex-induced expression of Bax and cytochrome c and increased the expression of B cell lymphoma-2(Bcl-2). Luteolin 13-16 BCL2 associated X, apoptosis regulator Rattus norvegicus 53-56 32035215-8 2020 Results further showed that luteolin pretreatment significantly repressed the METH-induced increases of PI3K, Akt, p-Akt, p53, Bax, caspase 3, normalized the ratio of p-Akt/Akt, and autophagy-related proteins (Beclin1, Atg5 and LC3-II) expression. Luteolin 28-36 BCL2 associated X, apoptosis regulator Rattus norvegicus 127-130