PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33412209-6	2021	However, U0126, a potent extracellular signal-regulated kinase 1/2 (Erk1/2) inhibitor, decreased PDGF-BB-induced LC3 expression, while rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR), increased it.	U 0126	9-14	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	113-116	
33748286-5	2021	Interestingly, we also found that the increased expression of microtubule-associated protein 1 light chain 3 (LC3)-II (a key marker of autophagy) and the decreased expression of p62 (autophagic substrate) induced by urinary proteins were reversed by U0126, suggesting autophagy was activated by ERK pathway.	U 0126	250-255	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	110-113	
28083623-9	2017	SFN was found to promote MAPK signaling, and inhibition of ERK activation using U0126 prevented SFN-induced LC3-II elevation and vesicle formation.	U 0126	80-85	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	108-111	
23743762-15	2013	However, the estradiol-enhanced LC3 protein expression was significantly suppressed by U0126 through inhibition of phosphorylation of extracellular signal-regulated kinase (ERK).	U 0126	87-92	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	32-35	
21768780-7	2011	Further, we found that both the MEK1/2 inhibitor U0126 and the JNK inhibitor SP600125, inhibited the atorvastatin-induced elevation of LC3-II, suggesting that the effect of atorvastatin on autophagy is mediated by the Erk and JNK pathways.	U 0126	49-54	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	135-138