PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25700356-8 2014 Additionally, U0126, an ERK signaling inhibitor, exerted a reversible effect on TGF-beta1-induced EMT and inhibited FOXM1 expression. U 0126 14-19 forkhead box M1 Homo sapiens 116-121 23285101-7 2012 But inhibition of ERK signaling by U0126 or PD98059 could reduce the level of FOXM1 in GRB7-overexpressing ovarian cancer cells, suggesting that GRB7, ERK and FOXM1 are regulated orderly. U 0126 35-40 forkhead box M1 Homo sapiens 78-83 23285101-7 2012 But inhibition of ERK signaling by U0126 or PD98059 could reduce the level of FOXM1 in GRB7-overexpressing ovarian cancer cells, suggesting that GRB7, ERK and FOXM1 are regulated orderly. U 0126 35-40 forkhead box M1 Homo sapiens 159-164 21858223-8 2011 Conversely, inhibition of FOXM1 expression by either thiostrepton or U0126 could significantly impair FOXM1 mediated oncogenic capacities. U 0126 69-74 forkhead box M1 Homo sapiens 26-31 21858223-8 2011 Conversely, inhibition of FOXM1 expression by either thiostrepton or U0126 could significantly impair FOXM1 mediated oncogenic capacities. U 0126 69-74 forkhead box M1 Homo sapiens 102-107 21858223-9 2011 However, the down-regulation of FOXM1 by either thiostrepton or U0126 required the presence of p53 in ovarian cancer cells. U 0126 64-69 forkhead box M1 Homo sapiens 32-37 16809346-4 2006 Furthermore, treatment of MCF-7 cells with the MEK inhibitor U0126, which blocks ERK1/2-dependent activation of FoxM1, also repressed ERalpha expression. U 0126 61-66 forkhead box M1 Homo sapiens 112-117 15671063-11 2005 Importantly, inhibition of Raf/MEK/MAPK signaling by U0126 led to suppression of FOXM1 target gene expression and delayed progression through G2/M, verifying the functional relevance of FOXM1 activation by MEK1. U 0126 53-58 forkhead box M1 Homo sapiens 81-86 15671063-11 2005 Importantly, inhibition of Raf/MEK/MAPK signaling by U0126 led to suppression of FOXM1 target gene expression and delayed progression through G2/M, verifying the functional relevance of FOXM1 activation by MEK1. U 0126 53-58 forkhead box M1 Homo sapiens 186-191