PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12689928-4	2003	UO126 modulated the levels of several intracellular proteins including B-cell lymphoma protein 2 (Bcl-2), myeloid cell leukemia-1 (Mcl-1) and caspase 8 homolog FLICE-inhibitory protein (cFLIP), and induced G2M cell-cycle arrest or apoptosis.	U 0126	0-5	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	106-129	
24299309-4	2014	Inhibition of ERK1/2 signaling by MEK inhibitor U0126 promoted cell death via increased activation of caspases, drop in mitochondrial membrane potential and downregulation of XIAP, cIAP2 and Mcl-1.	U 0126	48-53	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	191-196	
21660051-6	2011	Moreover, the ERK-dependent Noxa-myeloid cell leukemia-1 (Mcl-1) pathway is also involved, as silencing of Noxa expression was cardioprotective and U0126 abolished both the increase in Noxa expression and in Mcl-1 degradation.	U 0126	148-153	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	28-56	
21660051-6	2011	Moreover, the ERK-dependent Noxa-myeloid cell leukemia-1 (Mcl-1) pathway is also involved, as silencing of Noxa expression was cardioprotective and U0126 abolished both the increase in Noxa expression and in Mcl-1 degradation.	U 0126	148-153	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	58-63	
21660051-6	2011	Moreover, the ERK-dependent Noxa-myeloid cell leukemia-1 (Mcl-1) pathway is also involved, as silencing of Noxa expression was cardioprotective and U0126 abolished both the increase in Noxa expression and in Mcl-1 degradation.	U 0126	148-153	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	208-213	
12689928-4	2003	UO126 modulated the levels of several intracellular proteins including B-cell lymphoma protein 2 (Bcl-2), myeloid cell leukemia-1 (Mcl-1) and caspase 8 homolog FLICE-inhibitory protein (cFLIP), and induced G2M cell-cycle arrest or apoptosis.	U 0126	0-5	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	131-136	
12642693-5	2002	Coadminstration of UCN-01 with U0126 produced multiple perturbations in signal transduction/cell cycle regulatory pathways, including diminished expression of Bcr/Abl, Mcl-1, cylin D(1), and activation of JNK and p34(cdc2).	U 0126	31-36	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	168-173