PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22974512-5 2012 These actions were abolished by the antiandrogen bicalutamide and by the inhibitor of MAPK kinase (MEK1/2) U0126, suggesting that testosterone exerts its stimulatory effect on COX2/PGs through a non-classical mechanism that involves the presence of androgen receptors and MAPK1/2 activation. U 0126 107-112 prostaglandin G/H synthase 2 Mesocricetus auratus 176-180 19357132-7 2009 Because Bi and U0126, an inhibitor of the MAP kinase kinases 1 and 2 (MAP2K1/2), abolished testosterone actions on MAPK3/1 and PTGS2, our studies suggest that testosterone directly induces PTGS2/PGF(2alpha) in hamster Leydig cells via androgen receptors and a non-classical mechanism that involves MAPK3/1 activation. U 0126 15-20 prostaglandin G/H synthase 2 Mesocricetus auratus 127-132 19357132-7 2009 Because Bi and U0126, an inhibitor of the MAP kinase kinases 1 and 2 (MAP2K1/2), abolished testosterone actions on MAPK3/1 and PTGS2, our studies suggest that testosterone directly induces PTGS2/PGF(2alpha) in hamster Leydig cells via androgen receptors and a non-classical mechanism that involves MAPK3/1 activation. U 0126 15-20 prostaglandin G/H synthase 2 Mesocricetus auratus 189-194