PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33209885-5	2020	Studies have shown that MAPK may be related to MGMT expression, U0126 is a highly selective inhibitor of MEK1 and MEK2, which were crucial molecule in cascade of mitogen-activated protein kinase/extracellular signal regulated kinase (MAPK/ERK) pathway.	U 0126	64-69	O-6-methylguanine-DNA methyltransferase	Homo sapiens	47-51	
33209885-17	2020	Moreover, the results from RT-qPCR and Western blot showed that U0126 downregulated MGMT mRNA and MGMT protein expression via blocking MAPK/ERK pathway.	U 0126	64-69	O-6-methylguanine-DNA methyltransferase	Homo sapiens	84-88	
33209885-17	2020	Moreover, the results from RT-qPCR and Western blot showed that U0126 downregulated MGMT mRNA and MGMT protein expression via blocking MAPK/ERK pathway.	U 0126	64-69	O-6-methylguanine-DNA methyltransferase	Homo sapiens	98-102	
33209885-18	2020	Furthermore, after transfection with an MGMT expression plasmid, overexpression of MGMT restored U0126-induced chemosensitivity to TMZ in HCC cells.	U 0126	97-102	O-6-methylguanine-DNA methyltransferase	Homo sapiens	40-44	
33209885-18	2020	Furthermore, after transfection with an MGMT expression plasmid, overexpression of MGMT restored U0126-induced chemosensitivity to TMZ in HCC cells.	U 0126	97-102	O-6-methylguanine-DNA methyltransferase	Homo sapiens	83-87