PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16805793-5 2006 Nicotine phosphorylated cPKC-alpha, thereby increasing phosphorylation of ERK1/ERK2, as demonstrated by using Go6976, PD98059 or U0126. U 0126 129-134 mitogen-activated protein kinase 1 Bos taurus 79-83 17690170-6 2007 Moreover, this AngII-induced MKP-1 expression is reduced to 250 +/- 35% of controls (n = 3, P < 0.01) in the presence of U0126, an inhibitor of ERK1/2 phosphorylation, suggesting an involvement of the ERK1/2 MAPK pathway in MKP-1 induction. U 0126 124-129 mitogen-activated protein kinase 1 Bos taurus 211-215 11483651-3 2001 The inhibitors of mitogen-activated protein kinase kinase 1/2 (MEK1/2) activation, PD98059 (0.1-50 microM) and UO126 (0.1-10 microM), dose-dependently inhibited both ERK2 and Ser31 phosphorylation on TOH in response to AII, suggesting MEK1/2 involvement. U 0126 111-116 mitogen-activated protein kinase 1 Bos taurus 166-170 15192040-9 2004 Similarly, MAPK kinase-1 inhibitors PD98059 and U0126 each abolished TGFalpha-stimulated increases in IGFBP-3 mRNA levels. U 0126 48-53 mitogen-activated protein kinase 1 Bos taurus 11-15 14691048-12 2004 PAF MAPK activation was also inhibited by WEB2086, pertussis toxin (PTX), genistein, wortmannin, LY294002, PD98059 and UO126 in bovine neutrophils. U 0126 119-124 mitogen-activated protein kinase 1 Bos taurus 4-8 12506081-7 2003 U0126, an inhibitor of mitogen-activated protein kinase (MAPK) signaling, inhibited wound healing, with or without exposure to an EF. U 0126 0-5 mitogen-activated protein kinase 1 Bos taurus 57-61 15317664-9 2004 U0126 (10 muM) completely inhibited carbachol-induced ERK1/2 MAPK phosphorylation but did not significantly affect carbachol-induced upregulation of GAPDH and SMA expression, suggesting that the ERK1/2 MAPK pathway was not the underlying mechanism. U 0126 0-5 mitogen-activated protein kinase 1 Bos taurus 61-65 15317664-9 2004 U0126 (10 muM) completely inhibited carbachol-induced ERK1/2 MAPK phosphorylation but did not significantly affect carbachol-induced upregulation of GAPDH and SMA expression, suggesting that the ERK1/2 MAPK pathway was not the underlying mechanism. U 0126 0-5 mitogen-activated protein kinase 1 Bos taurus 202-206