PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12009331-5 2002 U0126 conferred 37-77% (MMP-3) and 43-73% (MMP-13) suppression in human and 77-100% (MMP-3) and 96-100% (MMP-13) in bovine chondrocytes. U 0126 0-5 matrix metallopeptidase 13 Homo sapiens 43-49 12009331-5 2002 U0126 conferred 37-77% (MMP-3) and 43-73% (MMP-13) suppression in human and 77-100% (MMP-3) and 96-100% (MMP-13) in bovine chondrocytes. U 0126 0-5 matrix metallopeptidase 13 Homo sapiens 105-111 14755151-9 2004 Mitogen-activated protein (MAP) kinase inhibitors (U0126 and PD098059) also blocked the MMP-1, -3 and TIMP-1 secretion. U 0126 51-56 matrix metallopeptidase 13 Homo sapiens 88-97 14516792-7 2003 Gene and protein expression of other MMPs that regulate MMP-9, such as MMP-1 and MMP-13, were also up-regulated by TNF-alpha and inhibited by UO126, providing evidence that the MAPK pathway plays a fundamental role in the regulation of MMP-9 secretion by keratinocytes. U 0126 142-147 matrix metallopeptidase 13 Homo sapiens 81-87 19542681-4 2009 An ERK-MAPK pathway inhibitor (U0126), but not a p38 kinase inhibitor (SB203580) or a JNK inhibitor (SP600125), also selectively inhibited IL-1beta-induced MMP-13 production in HAC. U 0126 31-36 matrix metallopeptidase 13 Homo sapiens 156-162 18487224-8 2008 Again, U0126 almost inhibited the induction of MMP-13 in HEp-2 cells by stimulating CXCL12. U 0126 7-12 matrix metallopeptidase 13 Homo sapiens 47-53 17208315-4 2007 Extracellular signal-regulated kinases (ERK1/2)-MAPK pathway inhibitor, U0126, down-regulated ADAMTS-4 and MMP-13 induction by OSM. U 0126 72-77 matrix metallopeptidase 13 Homo sapiens 107-113