PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25226519-8 2014 Phospho-ERK activation was visibly blocked and the MMP-1, MMP-3, and MMP-13 mRNA and protein levels were lower than the corresponding levels in the CSD without U0126 group. U 0126 160-165 matrix metallopeptidase 13 Rattus norvegicus 69-75 22965193-6 2013 It was noted that HA + U0126 significantly reduced the levels of pERK, chondrocyte hypertrophic markers (COL10 and RUNX2) and degenerative markers (ADAMTs5 and MMP-13), however, increased the levels of chondrogenic markers (COL2) compared to untreated or the application of HA or U0126 alone. U 0126 23-28 matrix metallopeptidase 13 Rattus norvegicus 160-166 33939302-21 2021 In addition, ERK inhibitor U0126 treatment also decreased the TNF-alpha, IL-6, and IL-1betalevels and MMP-3, MMP-13, ADAMTS-5, ICAM-1, ERK and p-ERK expression in HG + IL-1beta treated rat synovial fibroblasts. U 0126 27-32 matrix metallopeptidase 13 Rattus norvegicus 109-115