PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23588115-9	2013	In HBAFb AG1478, GM6001, the ERK1/2-inhibitor U0126 and the p38 inhibitor SB203580 suppressed bradykinin-induced cell proliferation, but only SB203580 reduced myofibroblast differentiation.	U 0126	46-51	kininogen 1	Homo sapiens	94-104	
21867693-3	2011	Exposure of the human colonic myofibroblast cell line 18Co to TNF-alpha and bradykinin induced synergistic MMP-3 mRNA and protein expression, which were blocked by the preferential PKC inhibitors GF109203X and Go6983 and by the MEK inhibitor U0126.	U 0126	242-247	kininogen 1	Homo sapiens	76-86	
18036509-5	2008	In contrast, inhibition of MEK1/2 by U0126 resulted in significantly reduced CREB phosphorylation levels after B2 bradykinin, but not M3 mACh receptor activation.	U 0126	37-42	kininogen 1	Homo sapiens	114-124	
21426904-8	2011	Inhibition of MAP kinase kinase (MEK) with U0126 also blocked bradykinin-induced ERK1/2 phosphorylation.	U 0126	43-48	kininogen 1	Homo sapiens	62-72	
19074839-10	2008	In HNSCC cells, the bradykinin-induced expression of COX-2 was inhibited by the EGFR kinase inhibitor gefitinib or mitogen-activated protein kinase kinase inhibitors (PD98059 or U0126).	U 0126	178-183	kininogen 1	Homo sapiens	20-30	
19788733-16	2009	Treatment of the cells with toxin B-1470 and U0126 significantly reduced bradykinin-induced IL-8 release alone or in combination with the activators of PKA and Epac.	U 0126	45-50	kininogen 1	Homo sapiens	73-83	
15573401-7	2005	Pretreatment with U0126 (a MEK1/2 inhibitor) attenuated the p42/p44 MAPK phosphorylation and [3H]thymidine incorporation stimulated by BK, but had no effect on Akt activation.	U 0126	18-23	kininogen 1	Homo sapiens	135-137	
12086980-14	2002	Moreover, PD98059 and U0126 prolonged the bradykinin-induced hyperpolarization of porcine coronary arteries, without affecting the magnitude of the response.	U 0126	22-27	kininogen 1	Homo sapiens	42-52