PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32477939-0 2020 LncRNA UCA1 Induces Acquired Resistance to Gefitinib by Epigenetically Silencing CDKN1A Expression in Non-small-Cell Lung Cancer. Gefitinib 43-52 urothelial cancer associated 1 Homo sapiens 7-11 32477939-4 2020 In the present study, we found that the lncRNA UCA1 was upregulated in NSCLC tissues and cells with acquired gefitinib resistance, indicating the special role of UCA1 in gefitinib resistance. Gefitinib 109-118 urothelial cancer associated 1 Homo sapiens 47-51 32477939-4 2020 In the present study, we found that the lncRNA UCA1 was upregulated in NSCLC tissues and cells with acquired gefitinib resistance, indicating the special role of UCA1 in gefitinib resistance. Gefitinib 170-179 urothelial cancer associated 1 Homo sapiens 47-51 32477939-4 2020 In the present study, we found that the lncRNA UCA1 was upregulated in NSCLC tissues and cells with acquired gefitinib resistance, indicating the special role of UCA1 in gefitinib resistance. Gefitinib 170-179 urothelial cancer associated 1 Homo sapiens 162-166 32477939-5 2020 Knockdown of UCA1 promoted the sensitivity to gefitinib both in vitro and in vivo by suppressing cell proliferation and inducing apoptosis. Gefitinib 46-55 urothelial cancer associated 1 Homo sapiens 13-17 32477939-7 2020 Taking the obtained findings together, our study suggests that UCA1 is important for NSCLC to develop gefitinib resistance, and is a potential biomarker for gefitinib resistance and a therapeutic target for advanced NSCLC. Gefitinib 102-111 urothelial cancer associated 1 Homo sapiens 63-67 32477939-7 2020 Taking the obtained findings together, our study suggests that UCA1 is important for NSCLC to develop gefitinib resistance, and is a potential biomarker for gefitinib resistance and a therapeutic target for advanced NSCLC. Gefitinib 157-166 urothelial cancer associated 1 Homo sapiens 63-67 30784252-0 2019 Knockout of lncRNA UCA1 inhibits drug resistance to gefitinib via targeting STAT3 signaling in NSCLC. Gefitinib 52-61 urothelial cancer associated 1 Homo sapiens 19-23 26160838-5 2015 UCA1 knockdown restored gefitinib sensitivity in acquired resistant cells with non-T790M and inhibited the activation of the AKT/mTOR pathway and epithelial-mesenchymal transition (EMT). Gefitinib 24-33 urothelial cancer associated 1 Homo sapiens 0-4