PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12363040-0 2002 Induction of apoptosis and CD10/neutral endopeptidase expression by jaspamide in HL-60 line cells. jasplakinolide 68-77 membrane metalloendopeptidase Homo sapiens 27-31 12363040-0 2002 Induction of apoptosis and CD10/neutral endopeptidase expression by jaspamide in HL-60 line cells. jasplakinolide 68-77 membrane metalloendopeptidase Homo sapiens 32-53 12363040-2 2002 We characterized the jasplakinolide-induced loss of viability by programmed cell death in the HL-60 human promyelocytic leukemia cell line and found that this process was accompanied by neutral endopeptidase (NEP)/CD10 expression on the surface of the apoptotic cells. jasplakinolide 21-35 membrane metalloendopeptidase Homo sapiens 186-207 12363040-2 2002 We characterized the jasplakinolide-induced loss of viability by programmed cell death in the HL-60 human promyelocytic leukemia cell line and found that this process was accompanied by neutral endopeptidase (NEP)/CD10 expression on the surface of the apoptotic cells. jasplakinolide 21-35 membrane metalloendopeptidase Homo sapiens 209-212 12363040-2 2002 We characterized the jasplakinolide-induced loss of viability by programmed cell death in the HL-60 human promyelocytic leukemia cell line and found that this process was accompanied by neutral endopeptidase (NEP)/CD10 expression on the surface of the apoptotic cells. jasplakinolide 21-35 membrane metalloendopeptidase Homo sapiens 214-218 12363040-3 2002 HL-60 cells do not normally express detectable amounts of NEP/CD10 on their surface or intracytoplasmically, but upon jaspamide treatment, CD10 was synthesized de novo, its expression being inhibited by cycloheximide pretreatment. jasplakinolide 118-127 membrane metalloendopeptidase Homo sapiens 139-143 12363040-4 2002 Once synthesized, NEP/CD10 interfered with the jasplakinolide signal delivered to HL-60 cells. jasplakinolide 47-61 membrane metalloendopeptidase Homo sapiens 18-21 12363040-4 2002 Once synthesized, NEP/CD10 interfered with the jasplakinolide signal delivered to HL-60 cells. jasplakinolide 47-61 membrane metalloendopeptidase Homo sapiens 22-26 12363040-9 2002 Our findings suggest that the CD10 expression is related to the programmed cell death induction by jaspamide, and also with the process of granulocytic differentiation in HL-60 cells. jasplakinolide 99-108 membrane metalloendopeptidase Homo sapiens 30-34