PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21709443-10	2011	These data also suggest the novel finding that the enhanced antitumor activity of topotecan following low-dose exposure correlates to alterations in cell cycle and increased p21 expression.	Topotecan	82-91	H3 histone pseudogene 16	Homo sapiens	174-177	
9732400-4	1998	Prolonged exposure for 72 hr to high nanomolar to low micromolar concentrations of topotecan augmented p21 protein levels and induced G2/M arrest but failed to consistently alter BCL-2 and BAX protein levels, did not induce significant DNA/topoisomerase I complex formation and did not inhibit RNA synthesis.	Topotecan	83-92	H3 histone pseudogene 16	Homo sapiens	103-106	
20875401-7	2011	Furthermore, TPT-dependent induction of p53, p21 and apoptosis were found 24-72h after treatment and were increased by PJ34 both in PARP-1 proficient and silenced cells.	Topotecan	13-16	H3 histone pseudogene 16	Homo sapiens	45-48