PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34452247-2	2021	We used positron emission tomography (PET) with the metabolically stable P-gp/BCRP substrates (11C)tariquidar, (11C)erlotinib, and (11C)elacridar to assess whether a similar functional redundancy as at the BBB exists in the liver, where both transporters mediate the biliary excretion of drugs.	tariquidar	99-109	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	78-82	
20621487-1	2010	The aim of this study was to develop a positron emission tomography (PET) tracer based on the dual P-glycoprotein (P-gp) breast cancer resistance protein (BCRP) inhibitor tariquidar (1) to study the interaction of 1 with P-gp and BCRP in the blood-brain barrier (BBB) in vivo.	tariquidar	171-181	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	155-159	
33081568-0	2021	Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib.	tariquidar	98-108	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	33-38	
33081568-0	2021	Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib.	tariquidar	98-108	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	154-159	
33081568-4	2021	co-infusion of erlotinib and tariquidar by studying brain distribution of the model ABCB1/ABCG2 substrate [11C]erlotinib in mice and rhesus macaques with PET.	tariquidar	29-39	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	90-95	
33081568-9	2021	Co-infusion of erlotinib/tariquidar may potentially allow for complete ABCB1/ABCG2 inhibition at the BBB, while simultaneously achieving brain-targeted EGFR inhibition.	tariquidar	25-35	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	77-82	
31729540-10	2020	After tariquidar administration, brain uptake increased 3-fold and 8-fold in wild-type and Abcg2-/- mice, respectively, but did not increase further in Abcb1a/b-/- mice.	tariquidar	6-16	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	91-96	
20610168-2	2010	Methyl is a recently discovered BCRP-selective inhibitor, which is structurally derived from the potent P-glycoprotein (P-gp) inhibitor tariquidar.	tariquidar	136-146	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	32-36