PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31114158-9	2019	In addition, we found that emodin significantly enhanced PTX-induced apoptosis in A549 cells via increasing the expressions of Bax and active caspase 3 and decreasing the levels of Bcl-2, p-Akt and p-ERK.	Emodin	27-33	BCL2 apoptosis regulator	Homo sapiens	181-186	
33817118-6	2018	Furthermore, the generation of reactive oxygen species (ROS) was up-regulated in KLE cells upon treatment with emodin, while the anti-oxidant agent N-acetyl cysteine (NAC) can inhibit emodin-induced apoptosis and promote the activation of AKT and Bcl-2.	Emodin	111-117	BCL2 apoptosis regulator	Homo sapiens	247-252	
33817118-6	2018	Furthermore, the generation of reactive oxygen species (ROS) was up-regulated in KLE cells upon treatment with emodin, while the anti-oxidant agent N-acetyl cysteine (NAC) can inhibit emodin-induced apoptosis and promote the activation of AKT and Bcl-2.	Emodin	184-190	BCL2 apoptosis regulator	Homo sapiens	247-252	
33300068-7	2021	Compared with those after Abeta exposure alone, emodin ameliorated the dissipation of the mitochondrial membrane potential, inhibited the over-accumulation of reactive oxygen species, enhanced the expression levels of nuclear factor-erythroid-2-related factor 2 (Nrf2), haemeoxygenase-1, superoxide dismutase 1, Bcl-2 and catalase in addition to decreasing the expression levels of Bax.	Emodin	48-54	BCL2 apoptosis regulator	Homo sapiens	312-317	
32509181-12	2020	In addition, the combination treatment (emodin plus 5-Fu) induced cell apoptosis via inhibiting Bcl-2 and activating cleaved caspase3 and Bax.	Emodin	40-46	BCL2 apoptosis regulator	Homo sapiens	96-101	
31280208-0	2019	Peroxiredoxin V Inhibits Emodin-induced Gastric Cancer Cell Apoptosis via the ROS/Bcl2 Pathway.	Emodin	25-31	BCL2 apoptosis regulator	Homo sapiens	82-86