PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22399496-6	2012	In FLO-1 cells, wortmannin suppressed ataxia telangiectasia and Rad3-related protein (ATR)-checkpoint kinase 1 (CHK1)-mediated checkpoint and multiple DNA repair genes, whereas RAD51 and CHK2 were not affected.	Wortmannin	16-26	checkpoint kinase 2	Homo sapiens	187-191	
18289623-10	2008	Inhibition of ATM/ATR, PI3-kinase and Chk1/Chk2 by CGK733, wortmannin and DBH, respectively, attenuated the apoptotic response in p53(wt) but not p53(mt) cells.	Wortmannin	59-69	checkpoint kinase 2	Homo sapiens	43-47	
15668230-13	2005	Ionizing radiation-induced Chk2 phosphorylation was wortmannin-sensitive in ATM-defective cells with depleted ATR.	Wortmannin	52-62	checkpoint kinase 2	Homo sapiens	27-31	
15533933-7	2005	Consistent with ATM or ATR activation, hyperoxia induced wortmannin-sensitive phosphorylation of Chk1, Chk2, and p53.	Wortmannin	57-67	checkpoint kinase 2	Homo sapiens	103-107