PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35605789-9	2022	Furthermore, BPAF markedly reduced the levels of SIRT1 and PGC1alpha at 200 mg/kg/d while significantly increased AMPK phosphorylation in the testes at 50 and 200 mg/kg/d.	4,4'-hexafluorisopropylidene diphenol	13-17	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	114-118	
35605789-10	2022	In conclusion, our results provide novel in vivo data that BPAF can induce fetal Leydig cell dysfunction by interfering with steroidogenic networks and induce the formation of multinucleated gonocytes after suppressing the antioxidant defense system and reducing SIRT1 and PGC1alpha signals and increasing the phosphorylation of AMPK, which highlights the potential health risk of environmental exposure to BPAF in inducing male reproductive tract malformation.	4,4'-hexafluorisopropylidene diphenol	59-63	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	329-333