PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33621883-5	2021	Low concentrations of BPAF markedly increased the expression of G protein-coupled estrogen receptor (GPER1), c-Myc, CyclinD1 and c-Fos proteins, and enhanced phosphorylation of extracellular signal-regulated kinase (Erk) and protein kinase B (Akt) in SKBR-3 cells.	4,4'-hexafluorisopropylidene diphenol	22-26	G protein-coupled estrogen receptor 1	Homo sapiens	101-106	
33621883-9	2021	The findings showed that GPER1 could independently regulate BPAF-induced proliferation of SKBR-3 cells without requiring ERalpha.	4,4'-hexafluorisopropylidene diphenol	60-64	G protein-coupled estrogen receptor 1	Homo sapiens	25-30	
31981723-6	2020	Furthermore, BPAF exposure at concentrations from 8 to 1000 ng/ml results in an increase in G protein-coupled estrogen receptor (GPER) expression.	4,4'-hexafluorisopropylidene diphenol	13-17	G protein-coupled estrogen receptor 1	Homo sapiens	92-127	
31981723-6	2020	Furthermore, BPAF exposure at concentrations from 8 to 1000 ng/ml results in an increase in G protein-coupled estrogen receptor (GPER) expression.	4,4'-hexafluorisopropylidene diphenol	13-17	G protein-coupled estrogen receptor 1	Homo sapiens	129-133	
28858478-4	2017	Here, using a SKBR3 cell-based fluorescence competitive binding assay, we found six BPA analogues bound to GPER directly, with bisphenol AF (BPAF) and bisphenol B (BPB) displaying much higher (~9-fold) binding affinity than BPA.	4,4'-hexafluorisopropylidene diphenol	141-145	G protein-coupled estrogen receptor 1	Homo sapiens	107-111	
28858478-8	2017	Moreover, based on the results of Boyden chamber and wound-healing assays, BPAF and BPB displayed higher activity in promoting GPER mediated SKBR3 cell migration than BPA with the LOEC of 100 nM.	4,4'-hexafluorisopropylidene diphenol	75-79	G protein-coupled estrogen receptor 1	Homo sapiens	127-131	
28858478-9	2017	Overall, we found two BPA analogues BPAF and BPB could exert higher estrogenic effects than BPA via GPER pathway at nanomolar concentrations.	4,4'-hexafluorisopropylidene diphenol	36-40	G protein-coupled estrogen receptor 1	Homo sapiens	100-104