PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25760729-0	2015	DNA methylation of DKK3 modulates docetaxel chemoresistance in human nonsmall cell lung cancer cell.	Docetaxel	34-43	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	19-23	
34255218-9	2022	In summary, our study found the involvement of the circRNA_0006404/miR-346/DKK3/p-GP and circRNA_0000735/miR-546b/DKK4/p-GP axis in the tumor response to DTX.	Docetaxel	154-157	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	75-79	
25760729-3	2015	DKK3 has been proved to be downregulated by hypermethylation in docetaxel-resistant lung cancer cells.	Docetaxel	64-73	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	0-4	
25760729-4	2015	Upregulation of DKK3 can reverse the chemoresistance of docetaxel-resistant cell lines in vitro by growth inhibition and enhancement of apoptosis.	Docetaxel	56-65	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	16-20	
25760729-5	2015	Conversely, downregulation of DKK3 could induce parental human lung cancer cells insensitivity to docetaxel by promoting proliferative capacity and inhibiting apoptosis of cancer cells.	Docetaxel	98-107	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	30-34	
25760729-7	2015	All results suggested that epigenetic downregulation of DKK3 leads to docetaxel resistance in human nonsmall cell lung cancer (NSCLC) cells by increased expression of P-glycoprotein.	Docetaxel	70-79	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	56-60	
25760729-8	2015	DKK3 may reveal a novel molecular target for docetaxel resistance for NSCLC patients in the future.	Docetaxel	45-54	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	0-4	
25760729-2	2015	In this study, this laboratory detected that DNA methylation contributes to the downregulation of DKK3 in docetaxel resistance of human lung cancer cells and its possible biochemical mechanism.	Docetaxel	106-115	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	98-102