PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9180834-3	1997	In contrast, in vitro studied showed that the initial metabolite of docetaxel resulted from the hydroxylation of the tert-butyl of the lateral chain at C13 and that the same metabolites were formed in human and animal models.	Docetaxel	68-77	homeobox C13	Homo sapiens	152-155	
11901098-2	2002	In spite of their close chemical structure, the two drugs are oxidized by two different enzymes; CYP2C8 catalyzes the 6-hydroxylation on the taxane ring of paclitaxel, whereas CYP3A4 oxidizes docetaxel on the tert-butyl group of the lateral chain in C13.	Docetaxel	192-201	homeobox C13	Homo sapiens	250-253	
7915328-0	1994	Structure-activity studies of antitumor taxanes: synthesis of novel C-13 side chain homologated taxol and taxotere analogs.	Docetaxel	106-114	homeobox C13	Homo sapiens	68-72	
8548776-2	1996	A main docetaxel metabolite was generated by human liver microsomes in the presence of NADPH: retention time in high pressure liquid chromatography and its ion fragmentation in mass spectrometry were identical to those of the authentic derivative hydroxylated at the butyl group of the C13 side chain.	Docetaxel	7-16	homeobox C13	Homo sapiens	286-289