PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29286833-7	2019	Results: GW3965 pretreatment significantly ameliorated the degree of IRI associated with the effects of upregulating Abca1 expression, inhibiting NF-kappaB transcriptional activity, and downregulating TNF-alpha and IL-6 level.	GW 3965	9-15	tumor necrosis factor	Rattus norvegicus	201-210	
30366037-12	2018	The nuclear factor kappaB (NF-kappaB) and tumor necrosis factor alpha (TNF-alpha) expressions were increased in hypertensive rats and reduced by GW3965 treatment.	GW 3965	145-151	tumor necrosis factor	Rattus norvegicus	42-69	
30366037-12	2018	The nuclear factor kappaB (NF-kappaB) and tumor necrosis factor alpha (TNF-alpha) expressions were increased in hypertensive rats and reduced by GW3965 treatment.	GW 3965	145-151	tumor necrosis factor	Rattus norvegicus	71-80	
19295476-0	2009	Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages.	GW 3965	25-31	tumor necrosis factor	Rattus norvegicus	119-128	
19295476-2	2009	We previously reported that pretreatment of rats with the liver X receptor (LXR) agonist GW3965 reduced the liver injury associated with endotoxemia and attenuated the production of TNF-alpha by rat Kupffer cells.	GW 3965	89-95	tumor necrosis factor	Rattus norvegicus	182-191	
19295476-4	2009	Low doses of GW3965 (0.1 or 0.3 mg/kg) administered 30 min before infusion of LPS and peptidoglycan significantly attenuated the increase in plasma levels of the liver injury markers alanine aminotransferase and bilirubin (6 h) as well as the inflammatory mediators TNF-alpha (1 h) and prostaglandin E2 (6 h) associated with endotoxemia.	GW 3965	13-19	tumor necrosis factor	Rattus norvegicus	266-275	
19295476-7	2009	Phosphorylated p38 mitogen-activated protein kinase, which plays a major role in production of TNF-alpha at the posttranscriptional level, was attenuated by GW3965 treatment in Kupffer cells.	GW 3965	157-163	tumor necrosis factor	Rattus norvegicus	95-104	
16525352-9	2006	Subsequent in vitro studies in Kupffer cells demonstrated that exposure to GW3965 attenuated the LPS-induced release of tumor necrosis factor alpha and prostaglandin E2 in a dose-dependent manner.	GW 3965	75-81	tumor necrosis factor	Rattus norvegicus	120-147