PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35155225-10 2022 Taken together, this study demonstrated that crizotinib- and sunitinib-caused oxidative stress and apoptosis finally impaired hepatic function, which was strongly supported by the histopathological lesions and markedly increased levels of serum alanine aminotransferase, alkaline phosphatase and lactate dehydrogenase. Sunitinib 61-70 glutamic--pyruvic transaminase Homo sapiens 245-269 23964934-8 2013 Patients treated with sunitinib, as compared with those treated with pazopanib, had a higher incidence of fatigue (63% vs. 55%), the hand-foot syndrome (50% vs. 29%), and thrombocytopenia (78% vs. 41%); patients treated with pazopanib had a higher incidence of increased levels of alanine aminotransferase (60%, vs. 43% with sunitinib). Sunitinib 22-31 glutamic--pyruvic transaminase Homo sapiens 281-305