PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34593007-0 2021 PFKFB4 is overexpressed in clear-cell renal cell carcinoma promoting pentose phosphate pathway that mediates Sunitinib resistance. Sunitinib 109-118 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Mus musculus 0-6 34593007-11 2021 PFKFB4-knockdown overcame resistance to Sunitinib in vitro and in vivo both in xenograft and tail-vein injection murine models. Sunitinib 40-49 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Mus musculus 0-6 34593007-13 2021 Targeting PFKFB4 held promise to combat resistance to Sunitinib. Sunitinib 54-63 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Mus musculus 10-16